Description

(1S,2R)-2-Fluorocyclopentan-1-Amine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its defined stereochemistry, which is critical for imparting specific biological activity in advanced drug molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in medicinal chemistry and process research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Asymmetric Synthesis: Serves as a versatile chiral amine precursor for constructing complex, stereodefined molecular architectures.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for candidate drugs.
• Biochemical Research: Potential use as a ligand or probe in enzymatic and receptor-binding studies due to its fluorinated cyclopentane structure.

Basic Information

Product Name	(1S,2R)-2-Fluorocyclopentan-1-Amine Hydrochloride
CAS No.	932706-27-9
Molecular Formula	C5H11ClFN
Molecular Weight	139.60 g/mol
Synonyms	(1S,2R)-2-Fluorocyclopentylamine hydrochloride; (1S,2R)-2-Fluorocyclopentanamine hydrochloride; (1S,2R)-2-Fluoro-1-aminocyclopentane hydrochloride; trans-2-Fluorocyclopentylamine hydrochloride; (1S,2R)-1-Amino-2-fluorocyclopentane hydrochloride; 2-Fluorocyclopentan-1-amine hydrochloride, (1S,2R)-; (1S,2R)-2-F-CPA HCl
EINECS	Contact for details

Quality Control

Our (1S,2R)-2-Fluorocyclopentan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing chiral purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.