Description

4-Fluoro-2-Methyl-5-Nitrobenzonitrile is a versatile and high-value fluorinated aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique substitution pattern enables precise structural modifications. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes and enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring fluorinated nitrobenzonitrile chemistry.
• Academic & Industrial R&D: Used in exploratory chemistry to develop new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	4-Fluoro-2-Methyl-5-Nitrobenzonitrile
CAS No.	932375-18-3
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	5-Nitro-2-methyl-4-fluorobenzonitrile; 2-Methyl-4-fluoro-5-nitrobenzonitrile; 4-Fluoro-2-methyl-5-nitrobenzonitrile; Benzonitrile, 4-fluoro-2-methyl-5-nitro-; 932375-18-3
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methyl-5-Nitrobenzonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.