Description

1-Bromo-5-Fluoro-4-Nitro-2-Trifluoromethyl-Benzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromo, fluoro, nitro, and trifluoromethyl substituents, makes it a versatile precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and stability.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Cross-Coupling Reactions: The bromine atom is an excellent site for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro and fluorine groups allow for selective substitution, enabling precise molecular diversification.
• Chemical Research & Development: An essential reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	1-Bromo-5-Fluoro-4-Nitro-2-Trifluoromethyl-Benzene
CAS No.	932374-77-1
Molecular Formula	C7H2BrF4NO2
Molecular Weight	287.99 g/mol
Synonyms	2-Bromo-4-fluoro-5-nitrobenzotrifluoride; 4-Fluoro-5-nitro-2-(trifluoromethyl)bromobenzene; 5-Fluoro-4-nitro-2-trifluoromethylbromobenzene; Benzene, 1-bromo-5-fluoro-4-nitro-2-(trifluoromethyl)-; 2-Trifluoromethyl-4-fluoro-5-nitro bromobenzene; 1-Bromo-5-fluoro-4-nitro-2-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards and precise customer requirements. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all test results are available upon request, providing full traceability and quality assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.