Description

1,3-Difluoro-5-Methyl-2-Nitrobenzene is a high-purity fluorinated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of fluorine and nitro substituents, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoromethylnitrobenzene structure contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce fluorinated nitroaryl groups.
• Dye and Pigment Intermediate: Utilized in the manufacture of specialized colorants and imaging agents.

Basic Information

Product Name	1,3-Difluoro-5-Methyl-2-Nitrobenzene
CAS No.	932373-92-7
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	2-Nitro-1,3-difluoro-5-methylbenzene; 5-Methyl-1,3-difluoro-2-nitrobenzene; 1,3-Difluoro-5-methyl-2-nitro-benzene; 2,6-Difluoro-4-methylnitrobenzene; Benzene, 1,3-difluoro-5-methyl-2-nitro-; 932373-92-7
EINECS	Contact for details

Quality Control

Our 1,3-Difluoro-5-Methyl-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.