Description

2,3-Difluoro-1-Methyl-4-Nitrobenzene is a high-value, multi-functional aromatic building block characterized by its strategically placed fluorine atoms and nitro group. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique substitution pattern enables precise molecular tuning. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides and pesticides, where the fluorine atoms improve biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic display and lighting materials.
• Polymer Modification: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, and optical properties.
• Organic Synthesis & Research: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution in R&D laboratories.
• Dye & Pigment Industry: Used in the development of novel fluorinated dyes with superior color fastness and performance.

Basic Information

Product Name	2,3-Difluoro-1-Methyl-4-Nitrobenzene
CAS No.	932373-72-3
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	1-Methyl-2,3-difluoro-4-nitrobenzene; 2,3-Difluoro-4-nitrotoluene; 4-Nitro-2,3-difluorotoluene; Toluene, 2,3-difluoro-4-nitro-; 2,3-Difluoro-p-nitrotoluene; NSC 876841
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-1-Methyl-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.