Description

Pentafluorophenyl 2-(Tetrahydro-2H-Pyran-4-Yloxy)Benzoate is a specialized fluorinated aromatic ester compound, serving as a high-value building block and activated intermediate in advanced organic synthesis. Its molecular architecture, featuring a pentafluorophenyl ester group, makes it a critical reagent for constructing complex molecules with enhanced stability and specific reactivity profiles. This compound is primarily utilized by pharmaceutical research and agrochemical development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents, including herbicides and fungicides, leveraging its fluorinated aromatic system.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials where fluorinated components impart desired properties like chemical resistance or thermal stability.
• Peptide and Protein Modification: Acts as an efficient acylating agent for modifying biomolecules, useful in bioconjugation and probe development.
• Chemical Biology Tool: Utilized in probe synthesis for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	Pentafluorophenyl 2-(Tetrahydro-2H-Pyran-4-Yloxy)Benzoate
CAS No.	926921-58-6
Molecular Formula	C18H15F5O4
Molecular Weight	390.31 g/mol
Synonyms	2-[(Oxan-4-yl)oxy]benzoic acid 2,3,4,5,6-pentafluorophenyl ester; Pentafluorophenyl 2-(tetrahydro-2H-pyran-4-yloxy)benzoate; 4-Pyranol, tetrahydro-, 2-benzoate, pentafluorophenyl ester; Benzoic acid, 2-[(tetrahydro-2H-pyran-4-yl)oxy]-, 2,3,4,5,6-pentafluorophenyl ester; PFP-THP-OBz ester; Pentafluorophenyl 2-(THPO)benzoate.
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 2-(Tetrahydro-2H-Pyran-4-Yloxy)Benzoate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.