Description

1,2,3-Trifluoro-5-Methoxy-4-Nitrobenzene is a high-value fluorinated aromatic building block characterized by its unique substitution pattern. This compound is essential for advanced organic synthesis, particularly in the development of complex molecules where the introduction of fluorine atoms and nitro/methoxy groups is critical for modulating electronic properties and biological activity. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for CNS-targeted and anti-infective therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms enhance metabolic stability and bioavailability.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated components in electronic display materials and organic semiconductors.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes with unique colorfastness and spectral properties.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.
• Academic & Contract Research: A valuable reagent for methodological studies in fluorination chemistry and heterocycle formation.

Basic Information

Product Name	1,2,3-Trifluoro-5-Methoxy-4-Nitrobenzene
CAS No.	925890-13-7
Molecular Formula	C7H3F3NO3
Molecular Weight	209.10 g/mol
Synonyms	4-Nitro-1,2,3-trifluoro-5-methoxybenzene; 1,2,3-Trifluoro-4-nitro-5-methoxybenzene; 5-Methoxy-1,2,3-trifluoro-4-nitrobenzene; Benzene, 1,2,3-trifluoro-5-methoxy-4-nitro-; 925890-13-7 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 1,2,3-Trifluoro-5-Methoxy-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.