Description

2-Chloro-4-Fluoro-3-Formylbenzonitrile is a high-purity, multi-functional aromatic intermediate of significant commercial importance. Its unique structure, featuring chloro, fluoro, formyl, and nitrile substituents, makes it a versatile building block for synthesizing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Serves as a critical building block for developing advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorine and nitrile groups.
• Ligand and Catalyst Development: Used in organic and organometallic chemistry to create specialized ligands and catalysts for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers with specific electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-4-Fluoro-3-Formylbenzonitrile
CAS No.	924626-91-5
Molecular Formula	C8H3ClFNO
Molecular Weight	183.57 g/mol
Synonyms	3-Formyl-2-chloro-4-fluorobenzonitrile; 2-Chloro-4-fluoro-3-formylbenzonitrile; 2-Chloro-4-fluorobenzaldehyde-3-carbonitrile; 3-Cyano-2-chloro-4-fluorobenzaldehyde; Benzonitrile, 2-chloro-4-fluoro-3-formyl-; (2-Chloro-4-fluoro-3-formylphenyl)carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-3-Formylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.