Description

trans-4-Fluoro-Cyclohexylamine Hydrochloride is a high-purity, synthetically valuable chiral amine salt. This compound serves as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring a rigid, fluorinated cyclohexylamine scaffold.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Peptidomimetics & Bioactive Molecules: Incorporated into peptide backbones to modulate conformation, stability, and receptor binding affinity.
• Material Science Research: Potential monomer or additive for creating specialized polymers with unique properties.
• Chemical Biology Probes: Used to develop molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	trans-4-Fluoro-Cyclohexylamine Hydrochloride
CAS No.	923596-01-4
Molecular Formula	C6H13ClFN
Molecular Weight	153.63 g/mol
Synonyms	trans-4-Fluorocyclohexanamine hydrochloride; (1r,4r)-4-Fluorocyclohexan-1-amine hydrochloride; 4-Fluorocyclohexylamine hydrochloride (trans); 4-Fluoro-trans-cyclohexylamine HCl; 4-Fluoro-trans-cyclohexylamine hydrochloride; trans-4-Fluorocyclohexylamine HCl; 4-Fluoro-cyclohexylamine hydrochloride (trans); 923596-01-4
EINECS	Contact for details

Quality Control

Our trans-4-Fluoro-Cyclohexylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.