Description

4-Fluoro-2-Isocyanatobenzonitrile is a versatile aromatic isocyanate building block, specifically functionalized with both a fluorine atom and a nitrile group. This unique structure makes it a critical intermediate for synthesizing advanced heterocyclic compounds and functional polymers with tailored properties. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated heterocycles, such as quinazolines and benzimidazoles, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polyurethanes, polyureas, and other polymers with specific thermal, chemical, or surface properties.
• Material Science Research: Employed in creating advanced functional materials, including liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing activity-based probes (ABPs) and other diagnostic tools due to its reactive isocyanate group, which can label specific biomolecules.

Basic Information

Product Name	4-Fluoro-2-Isocyanatobenzonitrile
CAS No.	923255-70-3
Molecular Formula	C8H3FN2O
Molecular Weight	162.12 g/mol
Synonyms	2-Isocyanato-4-fluorobenzonitrile; 4-Fluoro-2-isocyanato-benzonitrile; 4-Fluorobenzonitrile, 2-isocyanato-; 2-Fluoro-4-cyanophenyl isocyanate; Benzonitrile, 4-fluoro-2-isocyanato-; 4-Fluoro-2-isocyanato benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Isocyanatobenzonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.