Description

Cyclohexanecarbonitrile, 4,4-Difluoro- is a specialized fluorinated nitrile building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a rigid cyclohexane ring with a reactive nitrile group and two strategically placed fluorine atoms, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) and developing new fluorination methodologies.
• Fine Chemical Manufacturing: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Cyclohexanecarbonitrile, 4,4-Difluoro-
CAS No.	922728-21-0
Molecular Formula	C7H9F2N
Molecular Weight	145.15 g/mol
Synonyms	4,4-Difluorocyclohexanecarbonitrile; 4,4-Difluorocyclohexanenitrile; 4,4-Difluorocyclohexyl cyanide; trans/cis-4,4-Difluorocyclohexanecarbonitrile; (4,4-Difluorocyclohexyl)methanenitrile; 922728-21-0; 4,4-Difluoro-1-cyanocyclohexane
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonitrile, 4,4-Difluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider maintaining under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Isomer Ratio (GC/HPLC)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.