Description

Ethyl 1-(4-Methoxybenzyl)-5-Oxo-2-Phenyl-4-(Trifluoromethyl)-4,5-Dihydro-1H-Imidazol-4-Ylcarbamate is a high-value, complex heterocyclic compound featuring a trifluoromethyl group and an imidazolone core, making it a critical advanced intermediate in modern synthetic chemistry. Its precise molecular architecture is engineered to serve as a key building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is often sought to enhance metabolic stability and bioavailability. This compound is primarily targeted at research and development (R&D) scientists and process chemists in the pharmaceutical, agrochemical, and specialty fine chemical industries who require reliable, high-purity intermediates for their innovative synthesis programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Chemical Biology Probe: Acts as a scaffold or a tagged molecule in medicinal chemistry for studying enzyme inhibition and receptor-ligand interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial-scale production of fluorinated active ingredients.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	Ethyl 1-(4-Methoxybenzyl)-5-Oxo-2-Phenyl-4-(Trifluoromethyl)-4,5-Dihydro-1H-Imidazol-4-Ylcarbamate
CAS No.	921141-97-1
Molecular Formula	C21H20F3N3O4
Molecular Weight	435.40 g/mol
Synonyms	4-Carbethoxyamino-1-(4-methoxybenzyl)-2-phenyl-4-(trifluoromethyl)-4,5-dihydro-1H-imidazol-5-one; Ethyl N-[1-[(4-methoxyphenyl)methyl]-5-oxo-2-phenyl-4-(trifluoromethyl)-4,5-dihydro-1H-imidazol-4-yl]carbamate; 1-(4-Methoxybenzyl)-5-oxo-2-phenyl-4-(trifluoromethyl)-4,5-dihydro-1H-imidazole-4-carboxylic acid ethyl ester carbamate; 921141-97-1; 4-(Ethoxycarbonylamino)-1-(4-methoxybenzyl)-2-phenyl-4-(trifluoromethyl)-4,5-dihydro-1H-imidazol-5-one
EINECS	Contact for details

Quality Control

Every batch of Ethyl 1-(4-Methoxybenzyl)-5-Oxo-2-Phenyl-4-(Trifluoromethyl)-4,5-Dihydro-1H-Imidazol-4-Ylcarbamate is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards required for pharmaceutical and agrochemical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.