Description

1-Benzyloxy-3-Fluoro-2-Nitro-Benzene is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzyl-protected phenol and nitro-substituted aromatic ring system. This compound is critically important for its role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug molecules, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging its nitro-aromatic and fluorine-containing structure.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing protected phenolic and nitro-functionalized aromatic groups into more complex molecular architectures.
• Material Science Research: Investigated for potential use in the development of specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies in fluorination and nitro-group chemistry.

Basic Information

Product Name	1-Benzyloxy-3-Fluoro-2-Nitro-Benzene
CAS No.	920284-79-3
Molecular Formula	C₁₃H₁₀FNO₃
Molecular Weight	247.22 g/mol
Synonyms	3-Fluoro-2-nitrobenzylbenzene ether; 2-Nitro-3-fluorophenyl benzyl ether; Benzene, 1-(benzyloxy)-3-fluoro-2-nitro-; 1-(Benzyloxy)-3-fluoro-2-nitrobenzene; 3-Fluoro-2-nitrophenyl benzyl ether; (3-Fluoro-2-nitrophenoxy)methyl]benzene; 2-Nitro-3-fluorophenol benzyl ether
EINECS	Contact for details

Quality Control

Our 1-Benzyloxy-3-Fluoro-2-Nitro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.