Description

3-Fluoro-2-Iodobenzonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily utilized by R&D chemists and process development scientists in the life sciences sector for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the unique reactivity of the iodine and fluorine atoms.
• Material Science Research: Serves as a building block for creating specialized organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The iodine atom is highly reactive in palladium-catalyzed couplings (e.g., Suzuki, Sonogashira) for carbon-carbon bond formation.
• Fluorine Chemistry Studies: Used as a model compound in researching the effects of fluorine substitution on aromatic systems.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing complex chelating ligands used in homogeneous catalysis.

Basic Information

Product Name	3-Fluoro-2-Iodobenzonitrile
CAS No.	916792-62-6
Molecular Formula	C7H3FIN
Molecular Weight	262.01 g/mol
Synonyms	2-Iodo-3-fluorobenzonitrile; 3-Fluoro-2-iodobenzene carbonitrile; Benzonitrile, 3-fluoro-2-iodo-; 2-Cyano-6-fluoroiodobenzene; 3-Fluoro-2-iodo-benzonitrile; 916792-62-6 (CAS); 2-Iodo-3-fluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Iodobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.