Description

Benzonitrile, 2-Amino-5-Fluoro-4-Methyl- is a high-purity fluorinated aromatic nitrile building block, identified by CAS NO 916514-05-1. This compound is valued for its unique molecular structure, which combines an amino group, a fluorine atom, and a nitrile functionality on a methyl-substituted benzene ring, making it a versatile intermediate for advanced synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides that benefit from the stability and bioactivity of the fluorine substituent.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and polar functional groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Benzonitrile, 2-Amino-5-Fluoro-4-Methyl-
CAS No.	916514-05-1
Molecular Formula	C8H7FN2
Molecular Weight	150.16 g/mol
Synonyms	2-Amino-5-fluoro-4-methylbenzonitrile; 5-Fluoro-4-methyl-2-aminobenzonitrile; 2-Cyano-5-fluoro-4-methylaniline; 4-Methyl-5-fluoro-2-aminobenzonitrile; 2-Amino-4-methyl-5-fluorobenzonitrile; 5-Fluoro-2-amino-4-methylbenzonitrile; 2-Amino-5-fluoro-p-tolunitrile
EINECS	Contact for details

Quality Control

Our Benzonitrile, 2-Amino-5-Fluoro-4-Methyl- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.