Description

4-Methoxy-2-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research, due to the unique electronic properties imparted by the trifluoromethyl and methoxy substituents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Employed in the synthesis of specialty polymers with tailored thermal, chemical, or surface properties.
• Chemical Research & Development: A valuable building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Dye & Pigment Intermediate: Used in the synthesis of advanced colorants and fluorinated dyes.

Basic Information

Product Name	4-Methoxy-2-(Trifluoromethyl)Phenylacetonitrile
CAS No.	916420-88-7
Molecular Formula	C10H8F3NO
Molecular Weight	215.17 g/mol
Synonyms	2-(Trifluoromethyl)-4-methoxyphenylacetonitrile; (4-Methoxy-2-(trifluoromethyl)phenyl)acetonitrile; 4-Methoxy-α-(trifluoromethyl)benzeneacetonitrile; α-Cyano-4-methoxy-α,α,α-trifluoro-o-xylene; 2-(4-Methoxy-2-(trifluoromethyl)phenyl)acetonitrile; 4-Methoxy-2-trifluoromethylbenzyl cyanide
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.