Description

3,6-Dichloro-2-Fluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its unique halogen substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing character.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3,6-Dichloro-2-Fluorobenzonitrile
CAS No.	916420-65-0
Molecular Formula	C7H2Cl2FN
Molecular Weight	190.00 g/mol
Synonyms	2-Fluoro-3,6-dichlorobenzonitrile; 3,6-Dichloro-2-fluorobenzonitrile; 2-Fluoro-3,6-dichlorobenzene carbonitrile; Benzonitrile, 3,6-dichloro-2-fluoro-; 916420-65-0; 3,6-Dichloro-2-fluorobenzene-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 3,6-Dichloro-2-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.