Description

3-Methyl-5-(Trifluoromethoxy)Benzonitrile is a high-value, multi-functional aromatic nitrile building block. Its molecular structure, featuring a nitrile group and a trifluoromethoxy substituent on a methylated benzene ring, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functional groups and fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the lipophilicity and metabolic stability imparted by the trifluoromethoxy group.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy moiety enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Acts as a building block for advanced electronic materials, including liquid crystals for displays and organic light-emitting diode (OLED) components, where its rigid, substituted aromatic core is valuable.
• Specialty Polymer Modifier: Incorporated into polymer chains to alter physical properties such as thermal stability, chemical resistance, and refractive index for high-performance coatings and engineering plastics.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the creation of novel chemical libraries for screening.

Basic Information

Product Name	3-Methyl-5-(Trifluoromethoxy)Benzonitrile
CAS No.	916420-59-2
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	5-(Trifluoromethoxy)-3-methylbenzonitrile; 3-Methyl-5-(trifluoromethoxy)benzonitrile; 3-Methyl-α,α,α-trifluoro-p-anisonitrile; Benzonitrile, 3-methyl-5-(trifluoromethoxy)-; 3-Methyl-5-trifluoromethoxybenzonitrile; 5-Cyano-1-methyl-3-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-(Trifluoromethoxy)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most critical synthesis stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.