Description

2-Bromo-6-(Trifluoromethyl)Benzonitrile is a high-purity, multi-functional aromatic intermediate featuring both bromine and trifluoromethyl substituents. This compound is valued for its unique reactivity profile, enabling precise molecular construction in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig couplings.
• Fluorine Chemistry: An important reagent for introducing the trifluoromethyl moiety into complex molecules to modulate their lipophilicity, metabolic stability, and bioavailability.

Basic Information

Product Name	2-Bromo-6-(Trifluoromethyl)Benzonitrile
CAS No.	914637-35-7
Molecular Formula	C8H3BrF3N
Molecular Weight	250.02 g/mol
Synonyms	2-Bromo-α,α,α-trifluoro-o-tolunitrile; 6-Bromo-2-(trifluoromethyl)benzonitrile; 2-Bromo-6-trifluoromethylbenzonitrile; Benzonitrile, 2-bromo-6-(trifluoromethyl)-; o-Bromo-α,α,α-trifluorotoluonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.