Description

3-Bromo-5-(Trifluoromethoxy)Benzonitrile is a high-value, multi-functional aromatic building block characterized by its bromine and trifluoromethoxy substituents. This compound matters for its role in facilitating complex molecular construction, particularly in the synthesis of advanced materials and active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated and fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.
• Functional Polymer Monomer: Employed in the development of specialty polymers with tailored properties such as chemical resistance, thermal stability, and specific optical characteristics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethoxy)Benzonitrile
CAS No.	914635-52-2
Molecular Formula	C8H3BrF3NO
Molecular Weight	266.02 g/mol
Synonyms	3-Bromo-5-(trifluoromethoxy)benzonitrile; 5-Bromo-3-(trifluoromethoxy)benzonitrile; Benzonitrile, 3-bromo-5-(trifluoromethoxy)-; 914635-52-2; 3-Bromo-α,α,α-trifluoro-p-anisonitrile; 3-Bromo-5-trifluoromethoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Trifluoromethoxy)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality assurance supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.