Description

2,2'-((Perfluoropropane-2,2-Diyl)Bis(4,1-Phenylene))Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) is a high-value, fluorinated aryl boronic ester building block designed for advanced synthetic chemistry. This compound is critical for introducing perfluoroalkyl-substituted biphenyl motifs into complex molecular architectures via cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries to create novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for Suzuki-Miyaura cross-coupling reactions in the synthesis of potential drug candidates, especially those requiring fluorinated aromatic systems for improved metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, where the fluorine atoms and biphenyl core can contribute to pest selectivity and environmental persistence.
• Advanced Material Synthesis: Serves as a monomer or precursor for organic electronic materials, such as semiconductors for OLEDs or OFETs, where fluorination tunes electronic properties and enhances stability.
• Liquid Crystal & Polymer Chemistry: Incorporated into the backbone of specialty polymers and liquid crystal molecules to modify thermal properties, dielectric constants, and chemical resistance.
• Chemical Biology Probes: Enables the synthesis of fluorinated probes and tags for studying biological processes and protein interactions.
• Catalyst Ligand Development: Potential precursor for creating novel, fluorinated ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	2,2'-((Perfluoropropane-2,2-Diyl)Bis(4,1-Phenylene))Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane)
CAS No.	914359-47-0
Molecular Formula	C30H30B2F6O4
Molecular Weight	590.17 g/mol
Synonyms	1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2,2'-[2,2-bis(4-boronatophenyl)hexafluoropropane]di-; 2,2'-(Perfluoropropane-2,2-diylbis(4,1-phenylene))bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); 1,1'-(Perfluoroisopropylidene)bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene); Hexafluoro Bisphenol A Bis(Pinacol Boronate); Bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)hexafluoropropane; 4,4'-(Hexafluoroisopropylidene)diphenylenebis(boronic acid pinacol ester); 6F-BPA Bis(Pinacol Boronate)
EINECS	Contact for details

Quality Control

Our production of 2,2'-((Perfluoropropane-2,2-Diyl)Bis(4,1-Phenylene))Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for sensitive cross-coupling applications. Identity and purity are verified by advanced analytical techniques including NMR (1H, 13C, 19F) and HPLC. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent hydrolysis of the boronic ester groups. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.