Description

Benzeneacetonitrile, 2-Fluoro-Alpha,α-Dimethyl- is a specialized fluorinated organic nitrile building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a fluorine substituent and a quaternary carbon center adjacent to the nitrile group, makes it a valuable precursor for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a key intermediate for the development of novel active ingredients and fine chemicals requiring specific steric and electronic properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the fluorine atom and nitrile group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the development of advanced polymers and functional materials, where its fluorinated moiety can impart unique surface properties and chemical resistance.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing high-value, low-volume specialty chemicals for clients.

Basic Information

Product Name	Benzeneacetonitrile, 2-Fluoro-Alpha,α-Dimethyl-
CAS No.	913720-00-0
Molecular Formula	C10H10FN
Molecular Weight	163.19 g/mol
Synonyms	2-Fluoro-α,α-dimethylbenzeneacetonitrile; (2-Fluorophenyl)(isopropylidene)acetonitrile; 2-(2-Fluorophenyl)-2-methylpropanenitrile; α-Fluoro-α-methyl-2-methylbenzeneacetonitrile; 2-Fluoro-α-methylbenzenepropanenitrile; Fluorophenyl Dimethyl Acetonitrile; 913720-00-0; F-DMAN
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetonitrile, 2-Fluoro-Alpha,α-Dimethyl- is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.