Description

2-Fluoro-3-Iodo-4-Methyl-Benzonitrile is a high-purity, multi-functional halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and liquid crystals with specific optoelectronic properties.
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a substrate for studying halogen-metal exchange and nucleophilic aromatic substitution.
• Ligand and Catalyst Development: Useful for synthesizing complex chelating ligands for transition metal catalysis.

Basic Information

Product Name	2-Fluoro-3-Iodo-4-Methyl-Benzonitrile
CAS No.	909185-86-0
Molecular Formula	C8H5FIN
Molecular Weight	261.04 g/mol
Synonyms	2-Fluoro-3-iodo-4-methylbenzonitrile; 4-Methyl-2-fluoro-3-iodobenzonitrile; 3-Iodo-2-fluoro-4-methylbenzonitrile; Benzonitrile, 2-fluoro-3-iodo-4-methyl-; 909185-86-0; 2-F-3-I-4-Me-Bn; 2-Fluoro-3-iodo-p-tolunitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodo-4-Methyl-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for research and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.