Description

Methyl 3-(4-Fluoro-3-Nitrophenyl)Propanoate CAS NO 907602-44-2 is a high-value fluorinated aromatic ester building block, characterized by its nitro and fluoro substituents which are critical for modulating electronic and steric properties in advanced molecular architectures. This compound is essential for facilitating efficient synthetic routes in the development of complex active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds with targeted biological or physical characteristics.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Serves as a precursor for developing novel herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Liquid Crystal & OLED Material Development: Used in the synthesis of fluorinated aromatic cores for advanced electronic materials, contributing to improved performance in displays and lighting.
• Polymer Modification: Acts as a monomer or functionalization agent for creating specialty polymers with specific optical, thermal, or surface properties.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and molecular tags due to its reactive nitro group which can be further functionalized.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and nucleophilic aromatic substitution (SNAr).

Basic Information

Product Name	Methyl 3-(4-Fluoro-3-Nitrophenyl)Propanoate
CAS No.	907602-44-2
Molecular Formula	C10H10FNO4
Molecular Weight	227.19 g/mol
Synonyms	3-(4-Fluoro-3-nitrophenyl)propanoic acid methyl ester; Methyl 3-(4-fluoro-3-nitrophenyl)propionate; Methyl 4-fluoro-3-nitrohydrocinnamate; Propanoic acid, 3-(4-fluoro-3-nitrophenyl)-, methyl ester; 907602-44-2; Methyl β-(4-fluoro-3-nitrophenyl)propionate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(4-Fluoro-3-Nitrophenyl)Propanoate adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and chemical identity. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics. We support cGMP compliance for advanced intermediates and can provide materials suitable for research and non-GMP pilot-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.