Description

4-[5-(Trifluoromethyl)Pyridin-2-Yl]Benzylamine is a high-value, multi-functional aromatic amine building block featuring a pyridine core and a benzylamine moiety. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique trifluoromethyl-substituted heterocyclic structure imparts desirable biological activity and metabolic stability. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Active Ingredient Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyridine group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	4-[5-(Trifluoromethyl)Pyridin-2-Yl]Benzylamine
CAS No.	906352-74-7
Molecular Formula	C13H11F3N2
Molecular Weight	252.24 g/mol
Synonyms	2-[(4-Aminomethyl)phenyl]-5-(trifluoromethyl)pyridine; [4-[5-(Trifluoromethyl)-2-pyridinyl]phenyl]methanamine; 4-(5-Trifluoromethylpyridin-2-yl)benzylamine; 4-(5-(Trifluoromethyl)pyridin-2-yl)benzenemethanamine; 2-(4-(Aminomethyl)phenyl)-5-(trifluoromethyl)pyridine; α-Amino-4-[5-(trifluoromethyl)-2-pyridinyl]toluene
EINECS	Contact for details

Quality Control

Our 4-[5-(Trifluoromethyl)Pyridin-2-Yl]Benzylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.