Description

Esperamicin A1 is a potent enediyne antitumor antibiotic belonging to the esperamicin family. Its unique molecular architecture enables it to cause double-strand DNA cleavage, making it a compound of significant interest in biochemical research and oncology drug discovery. This high-purity compound is essential for researchers in pharmaceutical development, molecular biology, and biochemistry studying novel cancer therapeutics and DNA-damaging agents.

Application

• Anticancer Research: Serves as a critical reference standard and active agent in studies investigating novel chemotherapeutic mechanisms and DNA-targeting therapies.
• Biochemical Tool Compound: Used to induce site-specific DNA damage in molecular biology experiments to study DNA repair pathways and cellular responses.
• Pharmaceutical Development: Acts as a lead compound or benchmark in the discovery and development of new enediyne-based anticancer drugs.
• Mechanistic Studies: Employed in research to elucidate the structure-activity relationships (SAR) of enediyne antibiotics and their interaction with biological targets.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology, medicinal chemistry, and pharmacology.

Basic Information

Product Name	Esperamicin A1
CAS No.	99674-26-7
Molecular Formula	C58H84N2O21S4
Molecular Weight	1241.57 g/mol
Synonyms	Esperamicin A1; Esperamicin A; Esperamicin; Antibiotic BMY-28166; BMY 28166; BMY-28166; NSC 354646; Esperamicin A1 (BMY-28166)
EINECS	Contact for details

Quality Control

Our Esperamicin A1 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the product to equilibrate to room temperature in the unopened container before use to prevent moisture condensation. Store in a cool, dry, and well-ventilated area dedicated for research chemicals.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.