Description

2-Amino-3-Fluoro-5-Nitrobenzonitrile is a versatile and high-value aromatic nitrile derivative, distinguished by its unique trifunctional substitution pattern. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides and pesticides with enhanced activity and selectivity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Serves as a versatile scaffold for constructing complex heterocyclic compounds via reactions involving its amino, nitro, and cyano functional groups.
• Chemical Research & Development: Essential for academic and industrial R&D exploring new fluorinated aromatic compounds and their reactivity.
• Dye & Pigment Intermediate: Potential starting material for synthesizing specialized fluorinated dyes and colorants.

Basic Information

Product Name	2-Amino-3-Fluoro-5-Nitrobenzonitrile
CAS No.	99578-11-7
Molecular Formula	C7H4FN3O2
Molecular Weight	181.12 g/mol
Synonyms	3-Fluoro-5-nitro-2-aminobenzonitrile; 2-Amino-3-fluoro-5-nitrobenzenecarbonitrile; Benzonitrile, 2-amino-3-fluoro-5-nitro-; 99578-11-7; 3-Fluoro-2-amino-5-nitrobenzonitrile; 2-Amino-3-fluoro-5-nitro-benzonitrile; 5-Nitro-3-fluoroanthranilonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Fluoro-5-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be stored away from direct light exposure. Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.