Description

Epirubicin CAS NO 99570-29-3 is a semi-synthetic anthracycline antibiotic and a key chemotherapeutic agent. It is a critical active pharmaceutical ingredient (API) valued for its efficacy in treating various cancers. This compound is essential for pharmaceutical manufacturers, research institutions, and compounding facilities involved in oncology drug development and production.

Application

• Oncological Pharmaceutical Manufacturing: Primary use as the active ingredient in injectable chemotherapy formulations for breast cancer, gastric cancer, ovarian cancer, and lymphomas.
• Clinical Research & Drug Development: Serves as a reference standard and key intermediate in developing novel cancer therapies and combination treatment regimens.
• Pharmaceutical Compounding: Used in specialized pharmacy settings for preparing patient-specific doses in clinical oncology.
• Biochemical Research: Employed in laboratory studies to investigate mechanisms of action, DNA intercalation, topoisomerase II inhibition, and cellular apoptosis.
• Analytical Reference Standard: Utilized in quality control laboratories for HPLC, LC-MS, and other analytical methods to assay pharmaceutical products.

Basic Information

Item	Detail
Product Name	Epirubicin
CAS No.	99570-29-3
Molecular Formula	C₂₇H₂₉NO₁₁
Molecular Weight	543.52 g/mol
Synonyms	4'-Epidoxorubicin; 4'-Epiadriamycin; IMI-28; Pharmorubicin; Epirubicin Hydrochloride; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
EINECS	Contact for details

Quality Control

Our Epirubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis, to ensure it meets stringent pharmacopeial standards. A Certificate of Analysis (COA) documenting purity, potency, and compliance is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	Orange-red powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.