Description

2-Hydroxy-5-Nitro-3-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and nitro-substituted pyridine core. This compound matters for its role as a critical intermediate in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs), where its structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in antiviral and anti-inflammatory research.
• Agrochemical Synthesis: Serves as a core building block for next-generation herbicides and fungicides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Used in the development of specialty chemicals, ligands for catalysis, and advanced organic electronic materials.
• Chemical Reference Standard: Employed in analytical laboratories for method development and quality control testing.
• Organic Synthesis: A versatile reagent for introducing the 2-hydroxy-5-nitro-3-(trifluoromethyl)pyridyl moiety into more complex molecular architectures.

Basic Information

Product Name	2-Hydroxy-5-Nitro-3-(Trifluoromethyl)Pyridine
CAS No.	99368-66-8
Molecular Formula	C6H3F3N2O3
Molecular Weight	208.10 g/mol
Synonyms	5-Nitro-3-(trifluoromethyl)pyridin-2-ol; 3-(Trifluoromethyl)-5-nitropyridin-2-ol; 2-Pyridinol, 5-nitro-3-(trifluoromethyl)-; 5-Nitro-3-trifluoromethyl-2-pyridinol; 2-Hydroxy-5-nitro-3-trifluoromethylpyridine; 5-Nitro-3-(trifluoromethyl)-2-hydroxypyridine
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-Nitro-3-(Trifluoromethyl)Pyridine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.