Description

Pyrrolidine, 1-(2-Fluoro-3-Hydroxy-4-Methyl-1-Oxopentyl)-, (R*,S*)- (9Ci) is a fluorinated pyrrolidine derivative, a key chiral building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates fluorine and multiple functional groups to modulate the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in protease inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, high-performance pesticides and herbicides where the fluorine atom enhances bioavailability and environmental stability.
• Chemical Biology Probe Development: Serves as a versatile scaffold for constructing molecular probes to study enzyme function and biological pathways.
• Asymmetric Catalysis Ligand Precursor: The chiral centers make it a potential precursor for novel ligands used in asymmetric synthesis.
• Material Science Research: Investigated for incorporation into specialty polymers and advanced materials requiring specific stereochemistry and fluorination.

Basic Information

Product Name	Pyrrolidine, 1-(2-Fluoro-3-Hydroxy-4-Methyl-1-Oxopentyl)-, (R*,S*)- (9Ci)
CAS No.	99343-25-6
Molecular Formula	C10H18FNO3
Molecular Weight	219.26 g/mol
Synonyms	1-(2-Fluoro-3-hydroxy-4-methyl-1-oxopentyl)pyrrolidine; (R*,S*)-1-(2-Fluoro-3-hydroxy-4-methylpentanoyl)pyrrolidine; 2-Fluoro-3-hydroxy-4-methyl-1-pyrrolidin-1-ylpentan-1-one; 99343-25-6; Fluorinated pyrrolidine ketone; α-Fluoro-β-hydroxy acylpyrrolidine
EINECS	Contact for details

Quality Control

Our production of Pyrrolidine, 1-(2-Fluoro-3-Hydroxy-4-Methyl-1-Oxopentyl)-, (R*,S*)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.