Description

n-Benzyladriamycin-14-Valerate is a chemically modified derivative of the anthracycline antibiotic, adriamycin (doxorubicin). This compound is significant for its potential application as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis and study of novel anticancer agents and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anthracycline-based chemotherapeutic agents.
• Research & Development: Used as a reference standard or starting material in academic and industrial R&D for studying structure-activity relationships (SAR) in oncology.
• Anticancer Agent Development: Investigated for the development of prodrugs or targeted drug conjugates aimed at improving therapeutic efficacy and reducing systemic toxicity.
• Biochemical Research: Employed in studies exploring mechanisms of action, DNA intercalation, and topoisomerase II inhibition.
• Analytical Standard: Utilized as a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.

Basic Information

Product Name	n-Benzyladriamycin-14-Valerate
CAS No.	98983-21-2
Molecular Formula	C41H45NO13
Molecular Weight	759.80 g/mol
Synonyms	N-Benzyl-14-O-valeryladriamycin; N-Benzyl-14-valeryl doxorubicin; 14-O-Valeryl-N-benzyladriamycin; Adriamycin-14-valerate, N-benzyl derivative; Doxorubicin-14-valerate, N-benzyl derivative; N-Benzyl-14-valeryldoxorubicin; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione 14-valerate N-benzyl derivative
EINECS	Contact for details

Quality Control

Our n-Benzyladriamycin-14-Valerate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. For long-term storage, desiccate to protect from moisture. Allow the container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.