Description

Pyrilamine n-Oxide is a high-purity organic compound, specifically the N-oxide derivative of the antihistamine pyrilamine. This compound is of significant interest in advanced pharmaceutical research and development, serving as a crucial synthetic intermediate or reference standard. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis and analytical characterization of novel active pharmaceutical ingredients (APIs) and metabolites.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel antihistamine derivatives and other therapeutic agents.
• Metabolite Reference Standard: Used in analytical laboratories for the identification and quantification of pyrilamine metabolites in pharmacokinetic and bioanalytical studies.
• Chemical Research: Employed in academic and industrial research to study N-oxide chemistry, oxidation reactions, and structure-activity relationships (SAR).
• Process Development: Serves as a standard for developing and validating robust manufacturing processes for related pharmaceutical compounds.
• Analytical Method Development: Used as a high-purity standard to calibrate equipment and develop HPLC, LC-MS, or GC-MS methods.

Basic Information

Product Name	Pyrilamine n-Oxide
CAS No.	98982-99-1
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	N-(4-Methoxybenzyl)-N',N'-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine N-oxide; Pyrilamine N-Oxide; Mepyramine N-Oxide; Histadoxylamine N-Oxide; N-Oxide of N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine; 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, N-oxide
EINECS	Contact for details

Quality Control

Our Pyrilamine n-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from advanced techniques like HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.