Description

Butixocort 21-Propionate is a synthetic corticosteroid derivative, specifically a 21-propionate ester of butixocort. This compound is valued for its potent anti-inflammatory and immunosuppressive pharmacological activity, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by research institutions and pharmaceutical manufacturers developing topical and systemic corticosteroid therapies, as well as novel drug delivery systems.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potent topical corticosteroids for dermatological conditions like eczema, psoriasis, and dermatitis.
• Anti-inflammatory Drug Research: Used in preclinical and clinical research to develop new anti-inflammatory agents with optimized potency and reduced systemic side effects.
• Prodrug Development: Serves as a precursor for prodrug formulations designed to enhance skin penetration and localized therapeutic effect.
• Reference Standard: Employed as an analytical standard in quality control laboratories for HPLC, GC-MS, or NMR method development and validation.
• Veterinary Medicine: Potential application in formulating anti-inflammatory treatments for animal healthcare.

Basic Information

Product Name	Butixocort 21-Propionate
CAS No.	98449-05-9
Molecular Formula	C28H37FO7
Molecular Weight	504.59 g/mol
Synonyms	Butixocort Propionate; 9α-Fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxy-3,20-dioxopregna-1,4-diene-21-propionate; 9α-Fluoro-11β,21-dihydroxy-16α,17α-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione 21-propionate; Butixocort 21-propanoate; (11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione 21-propionate
EINECS	Contact for details

Quality Control

Our Butixocort 21-Propionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.