Description

Droloxifene Citrate is a selective estrogen receptor modulator (SERM) of significant pharmaceutical interest. This compound is valued for its research and development applications in the field of oncology and endocrinology. It is primarily utilized by pharmaceutical manufacturers, research institutions, and contract development organizations engaged in the development of therapeutic agents for hormone-related conditions.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of advanced therapeutic agents targeting estrogen receptors.
• Oncology Research: Investigated for its potential role in breast cancer research and development programs.
• Endocrine Disorder Studies: Used in preclinical and clinical research related to hormone-dependent conditions.
• Biochemical Research: Serves as a reference standard and active compound in biochemical assays and pharmacological studies.
• Academic & Contract Research: Employed by universities and CROs (Contract Research Organizations) for scientific discovery and drug development projects.
• GMP Manufacturing: Supplied as a starting material or intermediate for the production of active pharmaceutical ingredients (APIs) under Good Manufacturing Practice guidelines.

Basic Information

Product Name	Droloxifene Citrate
CAS No.	97752-20-0
Molecular Formula	C32H35NO8
Molecular Weight	561.62 g/mol
Synonyms	3-Hydroxytamoxifen Citrate; K 21060-E; Droloxifene Citrate Salt; (Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-1,2-diphenyl-1-buten-3-ol Citrate; 3-Hydroxy-N,N-dimethyl-4-[1,2-diphenyl-1-butenyl]phenethylamine Citrate; 3-OHT Citrate; 3-Hydroxytamoxifen Citrate Salt
EINECS	Contact for details

Quality Control

Our Droloxifene Citrate is manufactured and tested to meet high-purity standards suitable for pharmaceutical research and development. We employ rigorous analytical controls, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all relevant specifications. Our quality system supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a dry environment and sealed tightly after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.