Description

Idoxifene is a selective estrogen receptor modulator (SERM) with a well-defined pharmacological profile. This compound is of significant interest in pharmaceutical research and development, particularly for its potential applications in oncology and endocrinology. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Used in the synthesis of advanced therapeutic agents targeting hormone-responsive conditions.
• Biochemical Research: Acts as a key reference standard and tool compound in studies of estrogen receptor biology and signaling pathways.
• Oncology R&D: Investigated for its potential role in the development of novel treatments for breast cancer and other hormone-dependent cancers.
• Academic Research: Utilized in university and institutional laboratories for pharmacological and mechanistic studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Analytical Standard: Serves as a high-purity standard for method development and quality control in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	Idoxifene
CAS No.	116057-75-1
Molecular Formula	C29H35NO3
Molecular Weight	445.60 g/mol
Synonyms	Idoxifene; 1-[4-[2-(Dimethylamino)ethoxy]phenyl]-1-(4-iodophenyl)-2-phenylbut-1-ene; (E)-Idoxifene; Idoxifen; ICI 164384 analog; Z-4-Hydroxytamoxifen analog; Pyrrolidino-4-iodotamoxifen
EINECS	Contact for details

Quality Control

Our Idoxifene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.