Description

Tat 59 CAS NO 115767-74-3 is a high-purity chemical compound, also known as 4-Hydroxytamoxifen, which serves as a potent and selective estrogen receptor modulator (SERM). This compound is critical for advanced biochemical and pharmacological research, particularly in the study of hormone-responsive systems. It is an essential tool for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Research & Development: A key biochemical tool and reference standard in the study of estrogen receptor biology and the development of novel SERM-based therapeutics.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the synthesis and manufacturing of advanced pharmaceutical compounds targeting hormone-related conditions.
• Biochemical Assays: Employed as a critical reagent in cell-based assays and in vitro studies to investigate estrogen receptor signaling pathways and mechanisms of action.
• Academic & Institutional Research: Serves as a standard compound in university and institutional laboratories for fundamental research in endocrinology and cancer biology.
• Preclinical Studies: Utilized in animal model research to evaluate the efficacy and pharmacokinetics of potential drug candidates.
• Quality Control & Analytical Standards: Acts as a certified reference material (CRM) for method development and validation in analytical laboratories.

Basic Information

Product Name	Tat 59
CAS No.	115767-74-3
Molecular Formula	C26H29NO2
Molecular Weight	387.52 g/mol
Synonyms	4-Hydroxytamoxifen; (Z)-4-Hydroxytamoxifen; Afimoxifene; Metabolite E; ICI 79280; 1-[4-[2-(Dimethylamino)ethoxy]phenyl]-1-(4-hydroxyphenyl)-2-phenyl-1-butene; (Z)-1-(4-β-Dimethylaminoethoxyphenyl)-1-(4-hydroxyphenyl)-2-phenylbut-1-ene
EINECS	Contact for details

Quality Control

Our Tat 59 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support research and development with material that meets the stringent requirements for pharmaceutical intermediates and reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.