Description

Fadrozole is a potent, selective, and non-steroidal aromatase inhibitor, a key compound in pharmaceutical research and development. Its primary value lies in its ability to effectively block the conversion of androgens to estrogens, making it a critical tool for studying hormone-dependent processes. This makes it essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors. It is particularly valuable for applications in oncology research, endocrinology studies, and the development of therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting aromatase.
• Oncology Research: Used extensively in preclinical and clinical research for studying hormone-responsive cancers, such as breast cancer.
• Endocrinology Studies: A vital tool for investigating estrogen biosynthesis, hormone regulation, and related metabolic pathways.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Assay Development: Utilized in creating in-vitro screening assays to evaluate new aromatase inhibitor candidates.
• Veterinary Medicine Research: Applied in research concerning hormone-related conditions in animals.

Basic Information

Product Name	Fadrozole
CAS No.	102676-47-1
Molecular Formula	C₁₄H₁₃FN₄
Molecular Weight	256.28 g/mol
Synonyms	4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile; CGS 16949A; Afema; Letrozole intermediate; Aromatase Inhibitor CGS-16949A; Fadrozole hydrochloride (mono); CGP 47645
EINECS	Contact for details

Quality Control

Our Fadrozole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet stringent specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.