Description

1-(2-Fluoro-Phenyl)-Cyclopropanecarbonitrile is a versatile fluorinated cyclopropane derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring a nitrile group and a fluorinated aromatic ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the fluorine atom and the conformational rigidity of the cyclopropane ring.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers and liquid crystals with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(2-Fluoro-Phenyl)-Cyclopropanecarbonitrile
CAS No.	97009-38-6
Molecular Formula	C10H8FN
Molecular Weight	161.18 g/mol
Synonyms	2-Fluorophenylcyclopropanecarbonitrile; 1-(2-Fluorophenyl)cyclopropanecarbonitrile; (2-Fluorophenyl)cyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-(2-fluorophenyl)-; 1-(o-Fluorophenyl)cyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-Phenyl)-Cyclopropanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.