Description

3-Methyl-5-Trifluoromethylnitrobenzene is a high-purity, multi-functional aromatic intermediate essential for advanced organic synthesis. Its unique trifluoromethyl and nitro substituents on a methylated benzene ring make it a valuable building block for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Specialty Polymer Modifier: Incorporated into polymer chains to impart specific properties like chemical resistance, thermal stability, or altered refractive index.
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and pigments, where the nitro and trifluoromethyl groups influence color and fastness properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl structures.

Basic Information

Product Name	3-Methyl-5-Trifluoromethylnitrobenzene
CAS No.	96783-80-1
Molecular Formula	C9H6F3NO2
Molecular Weight	217.14 g/mol
Synonyms	1-Methyl-3-nitro-5-(trifluoromethyl)benzene; 3-Nitro-5-(trifluoromethyl)toluene; 5-Trifluoromethyl-3-nitrotoluene; 3-Methyl-α,α,α-trifluoro-5-nitrobenzene; 3-(Trifluoromethyl)-5-nitrotoluene; 5-Methyl-3-(trifluoromethyl)nitrobenzene; 3-Nitro-α,α,α-trifluoro-m-xylene
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-Trifluoromethylnitrobenzene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. Certificates of Analysis (COA) detailing specific batch results are provided and can be tailored to meet individual customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.