Description

Streptonigrone CAS NO 96684-38-7 is a potent quinone-based antibiotic and antitumor agent of significant research interest. Its primary value lies in its unique mechanism of action, which involves DNA intercalation and the generation of reactive oxygen species, leading to cytotoxic effects. This compound is essential for researchers in pharmaceutical development and academic biochemistry studying novel cancer therapeutics and antibiotic mechanisms.

Application

• Biomedical Research: As a reference standard and active agent in studies investigating DNA damage, apoptosis, and oxidative stress in cancer cell lines.
• Anticancer Drug Discovery: Serves as a lead compound or pharmacophore model for the synthesis and evaluation of new chemotherapeutic agents.
• Antibiotic Mechanism Studies: Used in microbiological research to study its effects against various bacterial strains and to understand resistance pathways.
• Biochemical Tool Compound: Employed in enzymology and molecular biology to probe specific biological pathways and protein interactions.
• Pharmaceutical Intermediate: Potential use in the synthesis of more complex derivatives with optimized pharmacological profiles.

Basic Information

Product Name	Streptonigrone
CAS No.	96684-38-7
Molecular Formula	C25H22N4O8
Molecular Weight	506.47 g/mol
Synonyms	Streptonigrin; Rufochromomycin; Bruneomycin; Antibiotic BA 180265; NSC 45383; 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid
EINECS	Contact for details

Quality Control

Our Streptonigrone is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment to prevent moisture absorption, which can compromise stability and purity.

Specification

Item	Specification
Appearance	Dark brown to black crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.