Description

21-Chloro-16β-Methyl-17-(1-Oxopropoxy)Pregna-1,4-Diene-3,20-Dione CAS NO 95796-50-2 is a high-purity synthetic steroid derivative, specifically a halogenated pregnadiene, designed for advanced pharmaceutical research and development. This compound is valued for its precise molecular structure, which serves as a critical intermediate in the synthesis of novel therapeutic agents targeting inflammatory and hormonal pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation corticosteroids and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid analogs and other steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new anti-inflammatory and immunosuppressive drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of steroid-based therapeutics.
• Biochemical Research: Investigated for its interaction with glucocorticoid and other steroid hormone receptors in preclinical studies.

Basic Information

Product Name	21-Chloro-16β-Methyl-17-(1-Oxopropoxy)Pregna-1,4-Diene-3,20-Dione
CAS No.	95796-50-2
Molecular Formula	C25H31ClO5
Molecular Weight	447.0 g/mol (approx.)
Synonyms	21-Chloro-16β-methylprednisolone 17-propionate; 16β-Methyl-21-chloroprednisolone 17-propionate; 21-Chloro-16β-methyl-17-propionyloxypregna-1,4-diene-3,20-dione; 95796-50-2; Prednisolone derivative, 21-chloro-16β-methyl-17-propionate; 16β-Methyl-21-chloro-δ1-pregnenolone 17-propionate
EINECS	Contact for details

Quality Control

Every batch of 21-Chloro-16β-Methyl-17-(1-Oxopropoxy)Pregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.