Description

3'-C-Methyldaunorubicin is a semi-synthetic anthracycline derivative, a structural analog of the potent anticancer agent daunorubicin. This compound is of significant interest in pharmaceutical research and development due to its potential as a key intermediate or active pharmaceutical ingredient (API) in novel oncology therapeutics. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in the synthesis and evaluation of new chemotherapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anthracycline-based anticancer drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships, mechanisms of action, and resistance profiles of anthracyclines.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and research and development (R&D) laboratories for method development and validation.
• API Development: Investigated as a potential active pharmaceutical ingredient for the formulation of injectable chemotherapeutics targeting various cancers.
• Bioconjugation Studies: Utilized in research exploring antibody-drug conjugates (ADCs) or other targeted drug delivery systems to enhance therapeutic efficacy and reduce side effects.

Basic Information

Product Name	3'-C-Methyldaunorubicin
CAS No.	95087-05-1
Molecular Formula	C₂₈H₃₁NO₁₀
Molecular Weight	541.55 g/mol
Synonyms	3'-C-Methyl-13-dihydrodaunorubicin; 3'-C-Methyl-13-dihydrodaunomycin; 4-Demethoxy-3'-methyl-13-dihydrodaunorubicin; 3'-Methyldaunorubicin; Daunorubicin, 3'-C-methyl-; (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,8,11-trihydroxy-3'-methoxy-8,9,10,11-tetrahydro-7H-tetracene-5,12-dione
EINECS	Contact for details

Quality Control

Our 3'-C-Methyldaunorubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure compliance with ICH guidelines and customer-specific requirements. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.