Description

[4-(Trifluoromethyl)Bicyclo[2.2.2]Octan-1-Yl]Methanol is a high-value, specialty organic compound featuring a rigid bicyclic framework and a trifluoromethyl group, making it a versatile building block for advanced chemical synthesis. Its unique structure offers significant potential for modifying the physical and chemical properties of target molecules, particularly in enhancing lipophilicity and metabolic stability. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in creating analogs with improved bioavailability and target selectivity.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents, where the trifluoromethyl group can contribute to enhanced biological activity and environmental persistence.
• Material Science: Acts as a precursor for specialty polymers, liquid crystals, or organic electronic materials, leveraging its rigid, three-dimensional structure.
• Fluorine Chemistry: A valuable reagent for introducing the CF3 group into complex molecular architectures, a common strategy in modern drug discovery.
• Catalyst & Ligand Development: Potential use in designing novel chiral ligands or organocatalysts for asymmetric synthesis.
• Academic & Industrial R&D: Employed in exploratory chemistry for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	[4-(Trifluoromethyl)Bicyclo[2.2.2]Octan-1-Yl]Methanol
CAS No.	94994-14-6
Molecular Formula	C10H15F3O
Molecular Weight	208.22 g/mol
Synonyms	4-(Trifluoromethyl)bicyclo[2.2.2]octane-1-methanol; 1-(Hydroxymethyl)-4-(trifluoromethyl)bicyclo[2.2.2]octane; (4-Trifluoromethylbicyclo[2.2.2]oct-1-yl)methanol; Bicyclo[2.2.2]octane-1-methanol, 4-(trifluoromethyl)-; 4-Trifluoromethyl-1-bicyclo[2.2.2]octylmethanol
EINECS	Contact for details

Quality Control

Our [4-(Trifluoromethyl)Bicyclo[2.2.2]Octan-1-Yl]Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to its chemical nature, it should be handled and stored separately from fluorides and strong alkalis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.