Description

(+)-Amosulalol CAS NO 94666-17-8 is a high-purity enantiomer of the β-adrenergic receptor antagonist amosulalol. This compound is of significant value in pharmaceutical research and development, particularly for studying stereoselective drug-receptor interactions and metabolic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in cardiovascular drug discovery, pharmacokinetic studies, and the synthesis of novel chiral therapeutic agents.

Application

• Pharmacological Research: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in cardiovascular research.
• Chiral Synthesis: Serves as a key building block for the synthesis of enantiomerically pure β-blockers and related compounds.
• Metabolic Studies: Employed in in vitro and in vivo studies to investigate the stereospecific metabolism of adrenergic antagonists.
• Analytical Standard: Functions as a high-purity calibration standard for HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Biochemical Assays: Utilized in receptor binding assays to determine the potency and selectivity of β-adrenergic ligands.
• Academic Research: Applied in university and institutional labs for fundamental studies in medicinal chemistry and pharmacology.

Basic Information

Product Name	(+)-Amosulalol
CAS No.	94666-17-8
Molecular Formula	C18H24N2O4S
Molecular Weight	364.46 g/mol
Synonyms	(+)-Amosulalol; (R)-Amosulalol; (R)-5-[1-Hydroxy-2-[[2-(4-methoxyphenyl)ethyl]amino]ethyl]-2-methylbenzenesulfonamide; YM-09538; (R)-YM-09538; Amosulalol (dextro isomer); (+)-YM-09538; (R)-form of Amosulalol
EINECS	Contact for details

Quality Control

Our (+)-Amosulalol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.