Description

Propranolol Laurate CAS NO 138656-55-0 is a long-acting prodrug ester of the widely used β-blocker, propranolol. This chemical modification is designed to provide a sustained-release profile, offering prolonged therapeutic effects from a single administration. It is primarily utilized in the pharmaceutical industry for the research and development of novel cardiovascular and anti-anxiety formulations, targeting improved patient compliance and controlled drug delivery systems.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of long-acting propranolol formulations for sustained drug release.
• Cardiovascular Research: Used in preclinical and clinical research for developing treatments for hypertension, angina, and cardiac arrhythmias with extended duration.
• Controlled-Release Drug Delivery Systems: A critical component in the design of implants, microspheres, or transdermal patches requiring prolonged β-blockade.
• Metabolic & Pharmacokinetic Studies: Employed in studies investigating the esterase-mediated hydrolysis and the resulting pharmacokinetic profile of propranolol.
• Reference Standard: Used as an analytical standard in quality control laboratories for the identification and quantification of propranolol laurate in finished products.

Basic Information

Product Name	Propranolol Laurate
CAS No.	138656-55-0
Molecular Formula	C28H47NO4
Molecular Weight	461.68 g/mol
Synonyms	1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol laurate; Propranolol dodecanoate; Propranolol lauryl ester; Lauric acid, ester with 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol; SQ 13991; ICI 139,101
EINECS	Contact for details

Quality Control

Our Propranolol Laurate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets high-purity standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.