Description

4-Allyl-2,3,5,6-Tetrafluorobenzonitrile is a specialized fluorinated aromatic nitrile building block, valued for its unique combination of a reactive allyl group and a highly electron-deficient tetrafluorobenzene core. This compound matters for its role in advanced material science and pharmaceutical research, where it serves as a key intermediate for constructing complex molecules with tailored electronic and physical properties. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty polymer industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Acts as a precursor for creating fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific properties such as chemical resistance, thermal stability, or low surface energy.
• Cross-coupling Reactions: The nitrile and allyl groups make it a versatile substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring the effects of polyfluorination on reaction pathways and molecular properties.

Basic Information

Product Name	4-Allyl-2,3,5,6-Tetrafluorobenzonitrile
CAS No.	94220-31-2
Molecular Formula	C10H5F4N
Molecular Weight	215.15 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-(2-propen-1-yl)benzonitrile; 4-Allyltetrafluorobenzonitrile; Benzonitrile, 4-allyl-2,3,5,6-tetrafluoro-; 4-(Prop-2-en-1-yl)-2,3,5,6-tetrafluorobenzonitrile; Tetrafluoro-4-allylbenzonitrile; 94220-31-2; 4-Allyl-2,3,5,6-tetrafluorobenzene carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Allyl-2,3,5,6-Tetrafluorobenzonitrile undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.