Description

17-Ketotrilostane is a synthetic steroid derivative with significant biochemical activity. This compound is primarily valued as a key intermediate in the research and development of pharmaceutical agents, particularly those targeting endocrine pathways. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors engaged in steroid chemistry and novel therapeutic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in laboratory studies to investigate steroid metabolism, enzyme inhibition, and related endocrine system functions.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Preclinical Development: Utilized in the early-stage development of potential therapeutic compounds for various hormonal disorders.

Basic Information

Product Name	17-Ketotrilostane
CAS No.	94152-62-2
Molecular Formula	C₂₀H₂₈O₃
Molecular Weight	316.44 g/mol
Synonyms	17-Ketotrilostane; Trilostane Metabolite; (8R,9S,10R,13S,14S,17S)-10,13-Dimethyl-17-(1-oxobutyl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-6,10,16-trione; WIN 24540; 3,17-Dioxo-4,5-epoxy-5α-androstane-2α-carbonitrile (related structure); 2α-Cyano-4α,5α-epoxy-3,17-dioxo-5α-androstane
EINECS	Contact for details

Quality Control

Our 17-Ketotrilostane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high standards for research and development use. A detailed Certificate of Analysis (COA) providing batch-specific results is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.