Description

Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11,17-Dihydroxy-16-Methyl-21-[(3-Sulfobenzoyl)Oxy]-, Monosodium Salt, (11Beta,16Beta)- is a high-purity synthetic corticosteroid derivative, specifically a water-soluble prodrug form. This compound is critical for pharmaceutical research and development, offering a key intermediate for advanced therapeutic formulations. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories specializing in anti-inflammatory and immunosuppressive agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potent topical and systemic corticosteroid APIs.
• Anti-inflammatory Drug Research: Used in preclinical and clinical research for developing new treatments for dermatological, ophthalmic, and rheumatic conditions.
• Prodrug Development: Exploited in formulation studies to enhance drug solubility, stability, and bioavailability.
• Reference Standard: Employed as an analytical standard in quality control laboratories for HPLC, LC-MS, and other chromatographic methods.
• Biochemical Research: Utilized in studies investigating glucocorticoid receptor interactions and downstream signaling pathways.

Basic Information

Item	Details
Product Name	Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11,17-Dihydroxy-16-Methyl-21-[(3-Sulfobenzoyl)Oxy]-, Monosodium Salt, (11Beta,16Beta)-
CAS No.	94135-40-7
Molecular Formula	C29H32FNaO9S
Molecular Weight	598.62 g/mol
Synonyms	Betamethasone Sodium Phosphate Related Compound C; 21-(3-Sulfobenzoyl)betamethasone Sodium Salt; 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-(3-sulfobenzoate) Sodium Salt; Betamethasone 21-(3-Sulfobenzoate) Sodium Salt; (11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-21-[(3-sulfobenzoyl)oxy]pregna-1,4-diene-3,20-dione Monosodium Salt
EINECS	Contact for details

Quality Control

Our Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11,17-Dihydroxy-16-Methyl-21-[(3-Sulfobenzoyl)Oxy]-, Monosodium Salt, (11Beta,16Beta)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identification by IR and NMR, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.