Description

11Beta,17-Dihydroxy-21,21-Diiodo-6Alpha-Methylpregna-1,4-Diene-3,20-Dione is a high-purity, synthetic steroid derivative with a complex molecular structure featuring diiodo substitution. This compound is a critical advanced intermediate in the pharmaceutical synthesis of potent corticosteroid drugs, valued for its precise stereochemistry and functional groups. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized anti-inflammatory and immunosuppressive agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel corticosteroid APIs (Active Pharmaceutical Ingredients).
• Steroid Research: Used in academic and industrial R&D to study structure-activity relationships (SAR) of halogenated steroids.
• Process Development: Serves as a reference standard and starting material for optimizing synthetic routes in process chemistry.
• Biochemical Studies: Employed in investigations targeting glucocorticoid and mineralocorticoid receptor interactions.

Basic Information

Product Name	11Beta,17-Dihydroxy-21,21-Diiodo-6Alpha-Methylpregna-1,4-Diene-3,20-Dione
CAS No.	94134-96-0
Molecular Formula	C22H28I2O5
Molecular Weight	626.27 g/mol
Synonyms	21,21-Diiodo-6α-methylprednisolone; 6α-Methyl-21,21-diiodoprednisolone; 11β,17,21-Trihydroxy-21,21-diiodo-6α-methylpregna-1,4-diene-3,20-dione; 21,21-Diiodo-6α-methyl-δ1-hydrocortisone; 94134-96-0; Diiodo Methylprednisolone Intermediate
EINECS	Contact for details

Quality Control

Our 11Beta,17-Dihydroxy-21,21-Diiodo-6Alpha-Methylpregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.