Description

9Beta,11Beta-Epoxy-16Alpha,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its complex, functionalized structure makes it invaluable for the synthesis of novel corticosteroid analogs and other biologically active molecules. This compound is primarily targeted at research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in the fields of endocrinology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel corticosteroid drugs and their derivatives.
• Research & Development: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) of steroid hormones.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized in studies investigating glucocorticoid and mineralocorticoid receptor interactions and signaling pathways.

Basic Information

Product Name	9Beta,11Beta-Epoxy-16Alpha,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione
CAS No.	94088-91-2
Molecular Formula	C21H26O7
Molecular Weight	390.43 g/mol
Synonyms	9β,11β-Epoxy-16α,17,21-trihydroxypregna-1,4-diene-3,20-dione; 16α,17,21-Trihydroxy-9β,11β-epoxypregna-1,4-diene-3,20-dione; 9β,11β-Epoxy-16α,17,21-trihydroxy-1,4-pregnadiene-3,20-dione; 16α-Hydroxy-9β,11β-epoxyprednisolone; A Steroid Epoxide Intermediate; Prednisolone 9β,11β-Epoxide Derivative
EINECS	Contact for details

Quality Control

Our 9Beta,11Beta-Epoxy-16Alpha,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.